2024
Lorenzon, Altea; Liu, Stephen; Jiang, Xiao; Gang, Grace; Stayman, J. Webster
Joint Material Decomposition and Scatter Estimation for Spectral CT Conference Forthcoming
International Conference on Image Formation in X-Ray Computed Tomography, vol. 8, Forthcoming.
BibTeX | Tags: MBIR, Scatter Estimation, Spectral X-ray/CT
@conference{nokey,
title = {Joint Material Decomposition and Scatter Estimation for Spectral CT},
author = {Altea Lorenzon and Stephen Liu and Xiao Jiang and Grace Gang and J. Webster Stayman},
year = {2024},
date = {2024-08-05},
booktitle = {International Conference on Image Formation in X-Ray Computed Tomography},
volume = {8},
keywords = {MBIR, Scatter Estimation, Spectral X-ray/CT},
pubstate = {forthcoming},
tppubtype = {conference}
}
Jiang, Xiao; Gang, Grace; Stayman, J. Webster
CT Material Decomposition using Spectral Diffusion Posterior Sampling Conference Forthcoming
8th International Conference on Image Formation in X-Ray Computed Tomography, vol. 8, Forthcoming.
Links | BibTeX | Tags: Machine Learning/Deep Learning, Spectral X-ray/CT
@conference{Jiang2024b,
title = {CT Material Decomposition using Spectral Diffusion Posterior Sampling},
author = {Xiao Jiang and Grace Gang and J. Webster Stayman },
url = {https://arxiv.org/abs/2402.03476},
year = {2024},
date = {2024-06-05},
urldate = {2024-06-05},
booktitle = {8th International Conference on Image Formation in X-Ray Computed Tomography},
volume = {8},
pages = {324-327},
keywords = {Machine Learning/Deep Learning, Spectral X-ray/CT},
pubstate = {forthcoming},
tppubtype = {conference}
}
Sandvold, Olivia; Proksa, Roland; Daerr, Heiner; Perkins, Amy; Brown, Kevin M; Shapira, Nadav; Köhler, Thomas; Stayman, J. Webster; Gang, Grace; Manjeshwar, Ravindra; Noël, Peter
Proc SPIE Medical Imaging, vol. 12925, 2024.
Links | BibTeX | Tags: Spectral X-ray/CT, System Assessment, System Design
@conference{Sandvold2024,
title = {Hybrid spectral CT system with clinical rapid kVp-switching X-ray tube and dual-layer detector for improved iodine quantification },
author = {Olivia Sandvold and Roland Proksa and Heiner Daerr and Amy Perkins and Kevin M Brown and Nadav Shapira and Thomas Köhler and J. Webster Stayman and Grace Gang and Ravindra Manjeshwar and Peter Noël},
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/12925/129251K/Hybrid-spectral-CT-system-with-clinical-rapid-kVp-switching-x/10.1117/12.3006451.full#_=_},
doi = {10.1117/12.3006451},
year = {2024},
date = {2024-02-22},
urldate = {2024-02-22},
booktitle = {Proc SPIE Medical Imaging},
volume = {12925},
pages = {129251K},
keywords = {Spectral X-ray/CT, System Assessment, System Design},
pubstate = {published},
tppubtype = {conference}
}
Jiang, Xiao; Tivnan, Matt; Zhang, Xiaoxuan; Gang, Grace; Stayman, J. Webster
Design optimization of a triple-layer flat-panel detector for three material decomposition Conference
Proc SPIE Medical Imaging, vol. 12925, 2024.
Links | BibTeX | Tags: Spectral X-ray/CT, System Design
@conference{Jiang2024,
title = {Design optimization of a triple-layer flat-panel detector for three material decomposition },
author = {Xiao Jiang and Matt Tivnan and Xiaoxuan Zhang and Grace Gang and J. Webster Stayman},
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/12925/3006385/Design-optimization-of-a-triple-layer-flat-panel-detector-for/10.1117/12.3006385.full#_=_},
doi = {10.1117/12.3006385},
year = {2024},
date = {2024-02-20},
urldate = {2024-02-20},
booktitle = {Proc SPIE Medical Imaging},
volume = {12925},
pages = {129250U },
keywords = {Spectral X-ray/CT, System Design},
pubstate = {published},
tppubtype = {conference}
}
2023
Zhang, Xiaoxuan; Stayman, J. Webster; Gang, Grace
Joint Temporal and Multi-energy Processing for Photon-Counting Fluoroscopy Conference
2023 IEEE Nuclear Science Symposium, Medical Imaging Conference and International Symposium on Room-Temperature Semiconductor Detectors (NSS MIC RTSD), IEEE, 2023.
Links | BibTeX | Tags: Spectral X-ray/CT
@conference{Zhang2023b,
title = {Joint Temporal and Multi-energy Processing for Photon-Counting Fluoroscopy},
author = {Xiaoxuan Zhang and J. Webster Stayman and Grace Gang},
url = {https://ieeexplore.ieee.org/abstract/document/10338707},
doi = {10.1109/NSSMICRTSD49126.2023.10338707},
year = {2023},
date = {2023-11-04},
booktitle = {2023 IEEE Nuclear Science Symposium, Medical Imaging Conference and International Symposium on Room-Temperature Semiconductor Detectors (NSS MIC RTSD)},
publisher = {IEEE},
keywords = {Spectral X-ray/CT},
pubstate = {published},
tppubtype = {conference}
}
Tivnan, Matt; Gang, Grace; Stayman, J. Webster
Proceedings of the 17th International Meeting on Fully 3D Image Reconstruction in Radiology and Nuclear Medicine, vol. 17, 2023.
Links | BibTeX | Tags: Spectral X-ray/CT, System Design
@conference{Tivnan2023c,
title = {Simulations of Immuno-Contrast CT to Optimize Spectral Instrumentation and Nanoparticle Contrast Agent Materials},
author = {Matt Tivnan and Grace Gang and J. Webster Stayman},
url = {https://aiai.jhu.edu/wp-content/uploads/Fully3D_2023_Tivnan.pdf},
year = {2023},
date = {2023-07-16},
booktitle = {Proceedings of the 17th International Meeting on Fully 3D Image Reconstruction in Radiology and Nuclear Medicine},
volume = {17},
pages = {486-489},
keywords = {Spectral X-ray/CT, System Design},
pubstate = {published},
tppubtype = {conference}
}
Jiang, Xiao; Zhang, Xiaoxuan; Stayman, J. Webster; Gang, Grace
Multi-material Decomposition with Triple Layer Flat-Panel Detector CBCT using Model-based and Deep Learning Approaches Honorable Mention Conference
Proceedings of the 17th International Meeting on Fully 3D Image Reconstruction in Radiology and Nuclear Medicine, vol. 17, 2023, (Poster Award).
Links | BibTeX | Tags: -Awards-, Machine Learning/Deep Learning, MBIR, Spectral X-ray/CT
@conference{Jiang2023b,
title = {Multi-material Decomposition with Triple Layer Flat-Panel Detector CBCT using Model-based and Deep Learning Approaches},
author = {Xiao Jiang and Xiaoxuan Zhang and J. Webster Stayman and Grace Gang},
url = {https://aiai.jhu.edu/wp-content/uploads/Fully3D_2023_Jiang.pdf},
year = {2023},
date = {2023-07-16},
urldate = {2023-07-16},
booktitle = {Proceedings of the 17th International Meeting on Fully 3D Image Reconstruction in Radiology and Nuclear Medicine},
journal = {Proceedings of the 16th International Meeting on Fully 3D Image Reconstruction in Radiology and Nuclear Medicine},
volume = {17},
note = {Poster Award},
keywords = {-Awards-, Machine Learning/Deep Learning, MBIR, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {conference}
}
Zhang, Xiaoxuan; Jiang, Xiao; Tivnan, Matt; Stayman, J. Webster; Gang, Grace
A Joint Processing Strategy for Image Quality Improvement in 3D Digital Subtraction Angiography Conference
Proceedings of the 17th International Meeting on Fully 3D Image Reconstruction in Radiology and Nuclear Medicine, vol. 17, 2023.
Links | BibTeX | Tags: MBIR, Spectral X-ray/CT
@conference{Zhang2023c,
title = {A Joint Processing Strategy for Image Quality Improvement in 3D Digital Subtraction Angiography},
author = {Xiaoxuan Zhang and Xiao Jiang and Matt Tivnan and J. Webster Stayman and Grace Gang},
url = {https://aiai.jhu.edu/wp-content/uploads/Fully3D_2023_Zhang.pdf
https://arxiv.org/abs/2310.10694},
year = {2023},
date = {2023-07-16},
urldate = {2023-07-01},
booktitle = {Proceedings of the 17th International Meeting on Fully 3D Image Reconstruction in Radiology and Nuclear Medicine},
volume = {17},
pages = {41-44},
keywords = {MBIR, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {conference}
}
Gang, Grace; Stayman, J. Webster
Proc SPIE Medical Imaging, vol. 12463, SPIE, 2023.
Links | BibTeX | Tags: Motion Compensation, Spectral X-ray/CT
@conference{nokey,
title = {Three-material decomposition using a dual-layer flat panel detector in the presence of soft tissue motion},
author = {Grace Gang and J. Webster Stayman},
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/12463/124630Y/Three-material-decomposition-using-a-dual-layer-flat-panel-detector/10.1117/12.2654443.full},
doi = {10.1117/12.2654443},
year = {2023},
date = {2023-04-07},
booktitle = {Proc SPIE Medical Imaging},
volume = {12463},
pages = {188-193},
publisher = {SPIE},
keywords = {Motion Compensation, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {conference}
}
Liu, Stephen; Zhou, Huanyi; Osgood, Greg M.; Demehri, Shadpour; Stayman, J. Webster; Zbijewski, Wojciech
Proc SPIE Medical Imaging, vol. 12463, SPIE, 2023.
Links | BibTeX | Tags: Extremities, MBIR, Spectral X-ray/CT
@conference{Liu2023,
title = {Quantitative dual-energy imaging of bone marrow edema using multi-source cone-beam CT with model-based decomposition},
author = {Stephen Liu and Huanyi Zhou and Greg M. Osgood and Shadpour Demehri and J. Webster Stayman and Wojciech Zbijewski},
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/12463/1246315/Quantitative-dual-energy-imaging-of-bone-marrow-edema-using-multi/10.1117/12.2654449.full},
doi = {10.1117/12.2654449},
year = {2023},
date = {2023-04-07},
booktitle = {Proc SPIE Medical Imaging},
volume = {12463},
pages = {228-234},
publisher = {SPIE},
keywords = {Extremities, MBIR, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {conference}
}
Jiang, Xiao; Stayman, J. Webster; Gang, Grace
Approaches for three material decomposition using a triple-layer flat-panel detector Conference
Proc SPIE Medical Imaging, vol. 12463, SPIE, 2023.
Links | BibTeX | Tags: Machine Learning/Deep Learning, Spectral X-ray/CT
@conference{Jiang2023,
title = {Approaches for three material decomposition using a triple-layer flat-panel detector},
author = {Xiao Jiang and J. Webster Stayman and Grace Gang},
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/12463/124630X/Approaches-for-three-material-decomposition-using-a-triple-layer-flat/10.1117/12.2654468.full},
doi = {10.1117/12.2654468},
year = {2023},
date = {2023-04-07},
booktitle = {Proc SPIE Medical Imaging},
volume = {12463},
pages = {182-187},
publisher = {SPIE},
keywords = {Machine Learning/Deep Learning, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {conference}
}
2022
Liu, Stephen; Tivnan, Matt; Osgood, Greg M.; Siewerdsen, Jeffrey H.; Stayman, J. Webster; Zbijewski, Wojciech
Model-based three-material decomposition in dual-energy CT using the volume conservation constraint Journal Article
In: Physics in Medicine and Biology, vol. 67, iss. 14, pp. 145006, 2022.
Links | BibTeX | Tags: MBIR, Spectral X-ray/CT
@article{Liu2022,
title = {Model-based three-material decomposition in dual-energy CT using the volume conservation constraint},
author = {Stephen Liu and Matt Tivnan and Greg M. Osgood and Jeffrey H. Siewerdsen and J. Webster Stayman and Wojciech Zbijewski},
url = {https://iopscience.iop.org/article/10.1088/1361-6560/ac7a8b/meta
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297826/},
doi = {10.1088/1361-6560/ac7a8b},
year = {2022},
date = {2022-07-08},
journal = {Physics in Medicine and Biology},
volume = {67},
issue = {14},
pages = {145006},
keywords = {MBIR, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {article}
}
Tivnan, Matt; Wang, Wenying; Gang, Grace; Stayman, J. Webster
Design Optimization of Spatial-Spectral Filters for Cone-Beam CT Material Decomposition Journal Article
In: IEEE Transactions on Medical Imaging, vol. 41, iss. 9, pp. 2399-2413, 2022.
Links | BibTeX | Tags: MBIR, Spectral X-ray/CT, System Design
@article{nokey,
title = {Design Optimization of Spatial-Spectral Filters for Cone-Beam CT Material Decomposition},
author = {Matt Tivnan and Wenying Wang and Grace Gang and J. Webster Stayman },
url = {https://pubmed.ncbi.nlm.nih.gov/35377842/, https://ieeexplore.ieee.org/abstract/document/9748122},
doi = {10.1109/TMI.2022.3164568},
year = {2022},
date = {2022-04-04},
journal = {IEEE Transactions on Medical Imaging},
volume = {41},
issue = {9},
pages = {2399-2413},
keywords = {MBIR, Spectral X-ray/CT, System Design},
pubstate = {published},
tppubtype = {article}
}
Tivnan, Matt; Gang, Grace; Zhang, Ruoqiao; Noël, Peter; Sulam, Jeremias; Stayman, J. Webster
Tunable neural networks for multi-material image formation from spectral CT measurements Conference
7th International Conference on Image Formation in X-Ray Computed Tomography, vol. 12304, SPIE, 2022.
Links | BibTeX | Tags: Machine Learning/Deep Learning, Spectral X-ray/CT
@conference{Tivnan2022b,
title = {Tunable neural networks for multi-material image formation from spectral CT measurements},
author = {Matt Tivnan and Grace Gang and Ruoqiao Zhang and Peter Noël and Jeremias Sulam and J. Webster Stayman},
url = {https://www.spiedigitallibrary.org/proceedings/Download?urlId=10.1117%2F12.2647138
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9627647/},
doi = {10.1117/12.2647138},
year = {2022},
date = {2022-03-01},
booktitle = {7th International Conference on Image Formation in X-Ray Computed Tomography},
volume = {12304},
publisher = {SPIE},
keywords = {Machine Learning/Deep Learning, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {conference}
}
2021
Wang, Wenying; Ma, Yiqun; Tivnan, Matt; Li, Junyuan; Gang, Grace; Zbijewski, Wojciech; Lu, Minghui; Zhang, Jin; Star-Lack, Josh; Colbeth, Richard; Stayman, J. Webster
High-resolution Model-based Material Decomposition in Dual-layer Flat-panel CBCT Journal Article
In: Medical Physics, vol. 48, iss. 10, pp. 6375-6387, 2021.
Links | BibTeX | Tags: High-Fidelity Modeling, High-Resolution CT, MBIR, Spectral X-ray/CT
@article{Wang2021b,
title = {High-resolution Model-based Material Decomposition in Dual-layer Flat-panel CBCT},
author = {Wenying Wang and Yiqun Ma and Matt Tivnan and Junyuan Li and Grace Gang and Wojciech Zbijewski and Minghui Lu and Jin Zhang and Josh Star-Lack and Richard Colbeth and J. Webster Stayman },
url = {https://pubmed.ncbi.nlm.nih.gov/34272890/, https://aapm.onlinelibrary.wiley.com/doi/full/10.1002/mp.14894},
doi = { 10.1002/mp.14894 },
year = {2021},
date = {2021-10-01},
journal = {Medical Physics},
volume = {48},
issue = {10},
pages = {6375-6387},
keywords = {High-Fidelity Modeling, High-Resolution CT, MBIR, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {article}
}
Tivnan, Matt; Wang, Wenying; Stayman, J. Webster
A prototype spatial–spectral CT system for material decomposition with energy‐integrating detectors Journal Article
In: Medical Physics, vol. 48, iss. 10, pp. 6401-6411, 2021.
Links | BibTeX | Tags: Sparse Sampling, Spectral X-ray/CT, System Assessment, System Design
@article{Tivnan2021b,
title = {A prototype spatial–spectral CT system for material decomposition with energy‐integrating detectors},
author = {Matt Tivnan and Wenying Wang and J. Webster Stayman },
url = {https://pubmed.ncbi.nlm.nih.gov/33964021/, https://aapm.onlinelibrary.wiley.com/doi/full/10.1002/mp.14930},
doi = {10.1002/mp.14930 },
year = {2021},
date = {2021-10-01},
journal = {Medical Physics},
volume = {48},
issue = {10},
pages = {6401-6411},
keywords = {Sparse Sampling, Spectral X-ray/CT, System Assessment, System Design},
pubstate = {published},
tppubtype = {article}
}
Tivnan, Matt; Gang, Grace; Cao, Wenchao; Shapira, Nadav; Noël, Peter; Stayman, J. Webster
High Sensitivity Iodine Imaging by Combining Spectral CT Technologies Best Paper Proceedings Article
In: 16th International Meeting on Fully 3D Image Reconstruction in Radiology and Nuclear Medicine, 2021, (Best Oral Presentation Award ).
Links | BibTeX | Tags: -Awards-, Analysis, MBIR, Spectral X-ray/CT, System Design
@inproceedings{nokey,
title = {High Sensitivity Iodine Imaging by Combining Spectral CT Technologies},
author = {Matt Tivnan and Grace Gang and Wenchao Cao and Nadav Shapira and Peter Noël and J. Webster Stayman },
url = {https://arxiv.org/abs/2103.15735},
year = {2021},
date = {2021-07-01},
urldate = {2021-07-01},
booktitle = {16th International Meeting on Fully 3D Image Reconstruction in Radiology and Nuclear Medicine},
volume = {16},
note = {Best Oral Presentation Award },
keywords = {-Awards-, Analysis, MBIR, Spectral X-ray/CT, System Design},
pubstate = {published},
tppubtype = {inproceedings}
}
Stayman, J. Webster; Tivnan, Matt; Wang, Wenying; Shapira, Nadav; Gang, Grace; Noël, Peter
Spectral CT using a fine grid structure and varying x‐ray incidence angle Journal Article
In: Medical Physics, 2021.
Abstract | Links | BibTeX | Tags: Customized Acquisition, Spectral X-ray/CT
@article{Stayman2021,
title = {Spectral CT using a fine grid structure and varying x‐ray incidence angle},
author = {J. Webster Stayman and Matt Tivnan and Wenying Wang and Nadav Shapira and Grace Gang and Peter Noël},
url = {https://aapm.onlinelibrary.wiley.com/doi/full/10.1002/mp.14853
https://pubmed.ncbi.nlm.nih.gov/34151442/},
doi = {10.1002/mp.14853},
year = {2021},
date = {2021-06-21},
journal = {Medical Physics},
abstract = {
},
keywords = {Customized Acquisition, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {article}
}
Zhao, Chumin; Liu, Stephen; Wang, Wenying; Herbst, Magdalena; Weber, Thomas; Vogt, Sebastian; Ritschl, Ludwig; Kappler, Steffen; Stayman, J. Webster; Siewerdsen, Jeffrey H.; Zbijewski, Wojciech
Effects of x-ray scatter in quantitative dual-energy imaging using dual-layer flat panel detectors Proceedings Article
In: SPIE Medical Imaging, pp. 115952A, International Society for Optics and Photonics, 2021.
Links | BibTeX | Tags: CBCT, High-Fidelity Modeling, Scatter Estimation, Spectral X-ray/CT
@inproceedings{Zhao2021,
title = {Effects of x-ray scatter in quantitative dual-energy imaging using dual-layer flat panel detectors},
author = {Chumin Zhao and Stephen Liu and Wenying Wang and Magdalena Herbst and Thomas Weber and Sebastian Vogt and Ludwig Ritschl and Steffen Kappler and J. Webster Stayman and Jeffrey H. Siewerdsen and Wojciech Zbijewski},
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11595/115952A/Effects-of-x-ray-scatter-in-quantitative-dual-energy-imaging/10.1117/12.2581822.full},
doi = {10.1117/12.2581822},
year = {2021},
date = {2021-02-15},
booktitle = {SPIE Medical Imaging},
volume = {11595},
pages = {115952A},
publisher = {International Society for Optics and Photonics},
keywords = {CBCT, High-Fidelity Modeling, Scatter Estimation, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {inproceedings}
}
Liu, Stephen; Siewerdsen, Jeffrey H.; Stayman, J. Webster; Zbijewski, Wojciech
Quantitative dual-energy imaging in the presence of metal implants using locally constrained model-based decomposition Proceedings Article
In: SPIE Medical Imaging, pp. 115951C, International Society for Optics and Photonics, 2021.
Links | BibTeX | Tags: MBIR, Metal Artifacts, Spectral X-ray/CT
@inproceedings{Liu2021,
title = {Quantitative dual-energy imaging in the presence of metal implants using locally constrained model-based decomposition},
author = {Stephen Liu and Jeffrey H. Siewerdsen and J. Webster Stayman and Wojciech Zbijewski},
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11595/115951C/Quantitative-dual-energy-imaging-in-the-presence-of-metal-implants/10.1117/12.2582277.full},
doi = {10.1117/12.2582277},
year = {2021},
date = {2021-02-15},
booktitle = {SPIE Medical Imaging},
volume = {11595},
pages = {115951C},
publisher = {International Society for Optics and Photonics},
keywords = {MBIR, Metal Artifacts, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {inproceedings}
}
2020
Liu, Stephen; Cao, Qian; Tivnan, Matt; Tilley, Steven; Siewerdsen, Jeffrey H.; Stayman, J. Webster; Zbijewski, Wojciech
Model-based dual-energy tomographic image reconstruction of objects containing known metal components Journal Article
In: Physics in Medicine and Biology, vol. 65, no. 24, pp. 245046, 2020.
Links | BibTeX | Tags: Artifact Correction, Known Components, MBIR, Metal Artifacts, Spectral X-ray/CT
@article{Liu2020bb,
title = {Model-based dual-energy tomographic image reconstruction of objects containing known metal components},
author = {Stephen Liu and Qian Cao and Matt Tivnan and Steven Tilley and Jeffrey H. Siewerdsen and J. Webster Stayman and Wojciech Zbijewski},
url = {https://pubmed.ncbi.nlm.nih.gov/33113519/},
doi = {10.1088/1361-6560/abc5a9},
year = {2020},
date = {2020-12-15},
journal = {Physics in Medicine and Biology},
volume = {65},
number = {24},
pages = {245046},
keywords = {Artifact Correction, Known Components, MBIR, Metal Artifacts, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {article}
}
Tivnan, Matt; Wang, Wenying; Stayman, J. Webster
A Preconditioned Algorithm for Model-Based Iterative CT Reconstruction and Material Decomposition from Spectral CT Data Journal Article
In: arXiv preprint , vol. arXiv:2010.01371, 2020.
Links | BibTeX | Tags: MBIR, Spectral X-ray/CT
@article{Tivnan2020bb,
title = {A Preconditioned Algorithm for Model-Based Iterative CT Reconstruction and Material Decomposition from Spectral CT Data},
author = {Matt Tivnan and Wenying Wang and J. Webster Stayman},
url = {https://arxiv.org/abs/2010.01371},
year = {2020},
date = {2020-10-03},
journal = {arXiv preprint },
volume = {arXiv:2010.01371},
keywords = {MBIR, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {article}
}
Ma, Yiqun; Wang, Wenying; Tivnan, Matt; Li, Junyuan; Lu, Minghui; Zhang, Jin; Star-Lack, Josh; Colbeth, Richard; Zbijewski, Wojciech; Stayman, J. Webster
High-Resolution Model-based Material Decomposition for Multi-Layer Flat-Panel Detectors Proceedings Article
In: International Conference on Image Formation in X-Ray Computed Tomography, 2020.
Links | BibTeX | Tags: CBCT, High-Fidelity Modeling, High-Resolution CT, MBIR, Spectral X-ray/CT
@inproceedings{Ma2020,
title = {High-Resolution Model-based Material Decomposition for Multi-Layer Flat-Panel Detectors},
author = {Yiqun Ma and Wenying Wang and Matt Tivnan and Junyuan Li and Minghui Lu and Jin Zhang and Josh Star-Lack and Richard Colbeth and Wojciech Zbijewski and J. Webster Stayman},
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643886/},
year = {2020},
date = {2020-08-01},
booktitle = {International Conference on Image Formation in X-Ray Computed Tomography},
keywords = {CBCT, High-Fidelity Modeling, High-Resolution CT, MBIR, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {inproceedings}
}
Stayman, J. Webster; Tivnan, Matt; Gang, Grace; Wang, Wenying; Shapira, Nadav; Noël, Peter
Grating-based Spectral CT using Small Angle X-ray Beam Deflections Proceedings Article
In: International Conference on Image Formation in X-Ray Computed Tomography, 2020.
Links | BibTeX | Tags: Spectral X-ray/CT, System Design
@inproceedings{Stayman2020,
title = {Grating-based Spectral CT using Small Angle X-ray Beam Deflections},
author = {J. Webster Stayman and Matt Tivnan and Grace Gang and Wenying Wang and Nadav Shapira and Peter Noël},
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643889/},
year = {2020},
date = {2020-08-01},
booktitle = {International Conference on Image Formation in X-Ray Computed Tomography},
keywords = {Spectral X-ray/CT, System Design},
pubstate = {published},
tppubtype = {inproceedings}
}
Tivnan, Matt; Wang, Wenying; Stayman, J. Webster
Multi-Contrast CT Imaging with a Prototype Spatial-Spectral Filter Proceedings Article
In: International Conference on Image Formation in X-Ray Computed Tomography, 2020.
Links | BibTeX | Tags: MBIR, Spectral X-ray/CT, System Design
@inproceedings{Tivnan2020b,
title = {Multi-Contrast CT Imaging with a Prototype Spatial-Spectral Filter },
author = {Matt Tivnan and Wenying Wang and J. Webster Stayman},
url = {https://pubmed.ncbi.nlm.nih.gov/33163990/},
year = {2020},
date = {2020-08-01},
booktitle = {International Conference on Image Formation in X-Ray Computed Tomography},
keywords = {MBIR, Spectral X-ray/CT, System Design},
pubstate = {published},
tppubtype = {inproceedings}
}
Liu, Stephen; Cao, Qian; Siewerdsen, Jeffrey H.; Stayman, J. Webster; Zbijewski, Wojciech
Three-material dual energy decomposition using a constrained model-based algorithm Proceedings Article
In: The Sixth International Conference on Image Formation in X-Ray Computed Tomography, 2020.
Links | BibTeX | Tags: High-Fidelity Modeling, MBIR, Spectral X-ray/CT
@inproceedings{Liu2020,
title = {Three-material dual energy decomposition using a constrained model-based algorithm},
author = {Stephen Liu and Qian Cao and Jeffrey H. Siewerdsen and J. Webster Stayman and Wojciech Zbijewski },
url = {https://www.researchgate.net/profile/Stephen-Liu-6/publication/345914209_Three-material_dual_energy_decomposition_using_a_constrained_model-based_algorithm/links/5fb1da0fa6fdcc9ae058148a/Three-material-dual-energy-decomposition-using-a-constrained-model-based-algorithm.pdf},
year = {2020},
date = {2020-08-01},
booktitle = {The Sixth International Conference on Image Formation in X-Ray Computed Tomography},
keywords = {High-Fidelity Modeling, MBIR, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {inproceedings}
}
Wang, Wenying; Tivnan, Matt; Gang, Grace; Ma, Yiqun; Lu, Minghui; Star-Lack, Josh; Colbeth, Richard; Zbijewski, Wojciech; Stayman, J. Webster
Model-based Material Decomposition with System Blur Modeling Honorable Mention Proceedings Article
In: SPIE Medical Imaging, pp. 113123Q, International Society for Optics and Photonics, 2020, (1st Place Poster Award ).
Links | BibTeX | Tags: -Awards-, CBCT, High-Resolution CT, MBIR, Spectral X-ray/CT
@inproceedings{Wang2020b,
title = {Model-based Material Decomposition with System Blur Modeling},
author = {Wenying Wang and Matt Tivnan and Grace Gang and Yiqun Ma and Minghui Lu and Josh Star-Lack and Richard Colbeth and Wojciech Zbijewski and J. Webster Stayman},
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641016/},
doi = {10.1117/12.2549549},
year = {2020},
date = {2020-03-16},
urldate = {2020-03-16},
booktitle = {SPIE Medical Imaging},
volume = {11312},
pages = {113123Q},
publisher = {International Society for Optics and Photonics},
note = {1st Place Poster Award },
keywords = {-Awards-, CBCT, High-Resolution CT, MBIR, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {inproceedings}
}
Wang, Wenying; Tivnan, Matt; Gang, Grace; Stayman, J. Webster
Prospective prediction and control of image properties in model-based material decomposition for spectral CT Proceedings Article
In: SPIE Medical Imaging, pp. 113121Z, International Society for Optics and Photonics, 2020.
Links | BibTeX | Tags: Analysis, MBIR, Regularization Design, Spectral X-ray/CT
@inproceedings{Wang2020,
title = {Prospective prediction and control of image properties in model-based material decomposition for spectral CT},
author = {Wenying Wang and Matt Tivnan and Grace Gang and J. Webster Stayman},
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7643888/},
doi = {10.1117/12.2549777},
year = {2020},
date = {2020-03-16},
booktitle = {SPIE Medical Imaging},
volume = {11312},
pages = {113121Z},
publisher = {International Society for Optics and Photonics},
keywords = {Analysis, MBIR, Regularization Design, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {inproceedings}
}
Tivnan, Matt; Wang, Wenying; Gang, Grace; Liapi, Eleni; Noël, Peter; Stayman, J. Webster
Combining spectral CT acquisition methods for high-sensitivity material decomposition Proceedings Article
In: SPIE Medical Imaging, pp. 1131218, International Society for Optics and Photonics, 2020.
Links | BibTeX | Tags: Analysis, MBIR, Spectral X-ray/CT
@inproceedings{Tivnan2020,
title = {Combining spectral CT acquisition methods for high-sensitivity material decomposition},
author = {Matt Tivnan and Wenying Wang and Grace Gang and Eleni Liapi and Peter Noël and J. Webster Stayman},
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7723360/},
doi = {10.1117/12.2550025},
year = {2020},
date = {2020-03-16},
booktitle = {SPIE Medical Imaging},
volume = {11312},
pages = {1131218},
publisher = {International Society for Optics and Photonics},
keywords = {Analysis, MBIR, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {inproceedings}
}
2019
Wang, Wenying; Tivnan, Matt; Gang, Grace; Tilley, Steven; Stayman, J. Webster
Generalized Local Impulse Response Prediction in Model-Based Material Decomposition of Spectral CT Honorable Mention Presentation
AAPM Annual Meeting: Young Investigator Symposium, 14.07.2019, (Young Investigator's Award Finalist ).
Links | BibTeX | Tags: -Awards-, Analysis, High-Fidelity Modeling, Regularization Design, Spectral X-ray/CT
@misc{Wang2019e,
title = {Generalized Local Impulse Response Prediction in Model-Based Material Decomposition of Spectral CT},
author = {Wenying Wang and Matt Tivnan and Grace Gang and Steven Tilley and J. Webster Stayman},
url = {https://w3.aapm.org/meetings/2019AM/programInfo/programAbs.php?sid=7994&aid=44687},
year = {2019},
date = {2019-07-14},
urldate = {2019-07-14},
howpublished = {AAPM Annual Meeting: Young Investigator Symposium},
note = {Young Investigator's Award Finalist },
keywords = {-Awards-, Analysis, High-Fidelity Modeling, Regularization Design, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {presentation}
}
Tivnan, Matt; Wang, Wenying; Tilley, Steven; Stayman, J. Webster
Designing Spatial-Spectral Filters for Spectral CT Best Paper Presentation
AAPM Annual Meeting: Best-in-Physics Award, 14.07.2019, (AAPM Best-in-Physics Award).
Links | BibTeX | Tags: -Awards-, Spectral X-ray/CT, System Design
@misc{Tivnan2019c,
title = {Designing Spatial-Spectral Filters for Spectral CT},
author = {Matt Tivnan and Wenying Wang and Steven Tilley and J. Webster Stayman},
url = {https://w3.aapm.org/meetings/2019AM/programInfo/programAbs.php?&shid[]=1482&sid=8008&aid=46979},
year = {2019},
date = {2019-07-14},
urldate = {2019-07-14},
howpublished = {AAPM Annual Meeting: Best-in-Physics Award},
note = {AAPM Best-in-Physics Award},
keywords = {-Awards-, Spectral X-ray/CT, System Design},
pubstate = {published},
tppubtype = {presentation}
}
Liu, Stephen; Tilley, Steven; Cao, Qian; Siewerdsen, Jeffrey H.; Stayman, J. Webster; Zbijewski, Wojciech
Known-component model-based material decomposition for dual energy imaging of bone compositions in the presence of metal implant Proceedings Article
In: International Meeting on Fully Three-Dimensional Image Reconstruction, Proc. SPIE , pp. 1107213, 2019.
Links | BibTeX | Tags: Extremities, Known Components, MBIR, Metal Artifacts, Spectral X-ray/CT
@inproceedings{Liu2019,
title = {Known-component model-based material decomposition for dual energy imaging of bone compositions in the presence of metal implant},
author = {Stephen Liu and Steven Tilley and Qian Cao and Jeffrey H. Siewerdsen and J. Webster Stayman and Wojciech Zbijewski},
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11072/2534725/Known-component-model-based-material-decomposition-for-dual-energy-imaging/10.1117/12.2534725.short
https://pubmed.ncbi.nlm.nih.gov/31359904/},
doi = {10.1117/12.2534725},
year = {2019},
date = {2019-06-02},
booktitle = {International Meeting on Fully Three-Dimensional Image Reconstruction, Proc. SPIE },
volume = {11072},
pages = {1107213},
keywords = {Extremities, Known Components, MBIR, Metal Artifacts, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {inproceedings}
}
Tivnan, Matt; Wang, Wenying; Tilley, Steven; Siewerdsen, Jeffrey H.; Stayman, J. Webster
Optimized spatial-spectral CT for multi-material decomposition Proceedings Article
In: 15th International Meeting on Fully Three-Dimensional Image Reconstruction, Proc. SPIE , pp. 1107211, 2019.
Links | BibTeX | Tags: Sparse Sampling, Spectral X-ray/CT, System Design
@inproceedings{Tivnan2019b,
title = {Optimized spatial-spectral CT for multi-material decomposition},
author = {Matt Tivnan and Wenying Wang and Steven Tilley and Jeffrey H. Siewerdsen and J. Webster Stayman },
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11072/2534333/Optimized-spatial-spectral-CT-for-multi-material-decomposition/10.1117/12.2534333.short},
doi = {10.1117/12.2534333},
year = {2019},
date = {2019-06-02},
booktitle = {15th International Meeting on Fully Three-Dimensional Image Reconstruction, Proc. SPIE },
volume = {11072},
pages = {1107211},
keywords = {Sparse Sampling, Spectral X-ray/CT, System Design},
pubstate = {published},
tppubtype = {inproceedings}
}
Wang, Wenying; Tilley, Steven; Tivnan, Matt; Stayman, J. Webster
Local response prediction in model-based CT material decomposition Proceedings Article
In: pp. 110720Z, 2019.
Links | BibTeX | Tags: Analysis, MBIR, Spectral X-ray/CT, System Assessment
@inproceedings{Wang2019c,
title = {Local response prediction in model-based CT material decomposition},
author = {Wenying Wang and Steven Tilley and Matt Tivnan and J. Webster Stayman },
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/11072/110720Z/Local-response-prediction-in-model-based-CT-material-decomposition/10.1117/12.2534437.short},
doi = {10.1117/12.2534437},
year = {2019},
date = {2019-06-02},
journal = {15th International Meeting on Fully Three-Dimensional Image Reconstruction, Proc. SPIE },
volume = {11072},
pages = {110720Z},
keywords = {Analysis, MBIR, Spectral X-ray/CT, System Assessment},
pubstate = {published},
tppubtype = {inproceedings}
}
Tivnan, Matt; Tilley, Steven; Stayman, J. Webster
Physical modeling and performance of spatial-spectral filters for CT material decomposition Proceedings Article
In: Proc. SPIE Medical Imaging, pp. 109481A-1-6, 2019.
Links | BibTeX | Tags: High-Fidelity Modeling, MBIR, Sparse Sampling, Spectral X-ray/CT, System Design
@inproceedings{Tivnan2019,
title = {Physical modeling and performance of spatial-spectral filters for CT material decomposition},
author = {Matt Tivnan and Steven Tilley and J. Webster Stayman},
url = {https://www.spiedigitallibrary.org/conference-proceedings-of-spie/10948/109481A/Physical-modeling-and-performance-of-spatial-spectral-filters-for-CT/10.1117/12.2513481.full},
doi = {10.1117/12.2513481},
year = {2019},
date = {2019-03-01},
booktitle = {Proc. SPIE Medical Imaging},
volume = {10948},
pages = {109481A-1-6},
keywords = {High-Fidelity Modeling, MBIR, Sparse Sampling, Spectral X-ray/CT, System Design},
pubstate = {published},
tppubtype = {inproceedings}
}
Tilley, Steven; Zbijewski, Wojciech; Stayman, J. Webster
Model-based material decomposition with a penalized nonlinear least-squares CT reconstruction algorithm Journal Article
In: Physics in Medicine and Biology, vol. 64, no. 3, pp. 035005–1-14, 2019.
Abstract | Links | BibTeX | Tags: High-Fidelity Modeling, MBIR, Spectral X-ray/CT
@article{Tilley2019,
title = {Model-based material decomposition with a penalized nonlinear least-squares CT reconstruction algorithm},
author = {Steven Tilley and Wojciech Zbijewski and J. Webster Stayman },
url = {https://pubmed.ncbi.nlm.nih.gov/30561382/},
doi = {10.1088/1361-6560/aaf973},
year = {2019},
date = {2019-02-01},
journal = {Physics in Medicine and Biology},
volume = {64},
number = {3},
pages = {035005–1-14},
abstract = {Spectral information in CT may be used for material decomposition to produce accurate reconstructions of material density and to separate materials with similar overall attenuation. Traditional methods separate the reconstruction and decomposition steps, often resulting in undesirable trade-offs (e.g. sampling constraints, a simplified spectral model). In this work, we present a model-based material decomposition algorithm which performs the reconstruction and decomposition simultaneously using a multienergy forward model. In a kV-switching simulation study, the presented method is capable of reconstructing iodine at 0.5 mg ml-1 with a contrast-to-noise ratio greater than two, as compared to 3.0 mg ml-1 for image domain decomposition. The presented method also enables novel acquisition methods, which was demonstrated in this work with a combined kV-switching/split-filter acquisition explored in simulation and physical test bench studies. This novel design used four spectral channels to decompose three materials: water, iodine, and gadolinium. In simulation, the presented method accurately reconstructed concentration value estimates with RMSE values of 4.86 mg ml-1 for water, 0.108 mg ml-1 for iodine and 0.170 mg ml-1 for gadolinium. In test-bench data, the RMSE values were 134 mg ml-1, 5.26 mg ml-1 and 1.85 mg ml-1, respectively. These studies demonstrate the ability of model-based material decomposition to produce accurate concentration estimates in challenging spatial/spectral sampling acquisitions.},
keywords = {High-Fidelity Modeling, MBIR, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {article}
}
2018
Stayman, J. Webster; Tilley, Steven
Model-based multi-material decomposition using spatial-spectral filters Proceedings Article
In: International Conference on Image Formation in X-Ray Computed Tomography, pp. 102-105, 2018.
Links | BibTeX | Tags: High-Fidelity Modeling, Sparse Sampling, Spectral X-ray/CT, System Design
@inproceedings{Stayman2018,
title = {Model-based multi-material decomposition using spatial-spectral filters},
author = {J. Webster Stayman and Steven Tilley},
url = {https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269151/},
year = {2018},
date = {2018-05-20},
booktitle = {International Conference on Image Formation in X-Ray Computed Tomography},
pages = {102-105},
keywords = {High-Fidelity Modeling, Sparse Sampling, Spectral X-ray/CT, System Design},
pubstate = {published},
tppubtype = {inproceedings}
}
Tilley, Steven; Zbijewski, Wojciech; Siewerdsen, Jeffrey H.; Stayman, J. Webster
A general reconstruction algorithm for model-based material decomposition Proceedings Article
In: Proc. SPIE Medical Imaging, pp. 1015731E-1-7, 2018, (Errata: The Huber penalty delta was 10^-3, not 10^3.).
Links | BibTeX | Tags: Sparse Sampling, Spectral X-ray/CT
@inproceedings{Tilley2018b,
title = {A general reconstruction algorithm for model-based material decomposition},
author = {Steven Tilley and Wojciech Zbijewski and Jeffrey H. Siewerdsen and J. Webster Stayman},
url = {https://aiai.jhu.edu/wp-content/uploads/spie2018-2.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891153/
https://www.spiedigitallibrary.org/conference-proceedings-of-spie/10573/2293776/A-general-CT-reconstruction-algorithm-for-model-based-material-decomposition/10.1117/12.2293776.full},
doi = {10.1117/12.2293776},
year = {2018},
date = {2018-02-15},
booktitle = {Proc. SPIE Medical Imaging},
volume = {10573},
pages = {1015731E-1-7},
note = {Errata: The Huber penalty delta was 10^-3, not 10^3.},
keywords = {Sparse Sampling, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {inproceedings}
}
2015
Zbijewski, Wojciech; Cao, Qian; Tilley, Steven; Sisniega, Alejandro; Stayman, J. Webster; Yorkston, John; Siewerdsen, Jeffrey H.
Quantitative Assessment Of Bone And Joint Health On A Dedicated Extremities Cone-Beam CT System. Journal Article
In: International journal of computer assisted radiology and surgery, vol. 10, no. Suppl 1, pp. S29–S31, 2015, ISSN: 1861-6429.
Links | BibTeX | Tags: CBCT, Extremities, Spectral X-ray/CT
@article{zbijewski2015quantitative,
title = {Quantitative Assessment Of Bone And Joint Health On A Dedicated Extremities Cone-Beam CT System.},
author = {Wojciech Zbijewski and Qian Cao and Steven Tilley and Alejandro Sisniega and J. Webster Stayman and John Yorkston and Jeffrey H. Siewerdsen },
url = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC4451217},
issn = {1861-6429},
year = {2015},
date = {2015-06-01},
journal = {International journal of computer assisted radiology and surgery},
volume = {10},
number = {Suppl 1},
pages = {S29--S31},
publisher = {NIH Public Access},
keywords = {CBCT, Extremities, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {article}
}
Zbijewski, Wojciech; Sisniega, Alejandro; Stayman, J. Webster; Thawait, Gaurav K.; Packard, Nathan; Yorkston, John; Demehri, Shadpour; Fritz, Jan; Siewerdsen, Jeffrey H.
Dual-energy imaging of bone marrow edema on a dedicated multi-source cone-beam CT system for the extremities Proceedings Article
In: Hoeschen, Christoph; Kontos, Despina; Flohr, Thomas G. (Ed.): SPIE Medical Imaging, pp. 94120V, International Society for Optics and Photonics 2015.
Links | BibTeX | Tags: CBCT, Extremities, Spectral X-ray/CT
@inproceedings{zbijewski2015dual,
title = {Dual-energy imaging of bone marrow edema on a dedicated multi-source cone-beam CT system for the extremities},
author = {Wojciech Zbijewski and Alejandro Sisniega and J. Webster Stayman and Gaurav K. Thawait and Nathan Packard and John Yorkston and Shadpour Demehri and Jan Fritz and Jeffrey H. Siewerdsen},
editor = {Christoph Hoeschen and Despina Kontos and Thomas G. Flohr },
url = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?doi=10.1117/12.2082304},
doi = {10.1117/12.2082304},
year = {2015},
date = {2015-03-01},
booktitle = {SPIE Medical Imaging},
pages = {94120V},
organization = {International Society for Optics and Photonics},
keywords = {CBCT, Extremities, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {inproceedings}
}
Sisniega, Alejandro; Zbijewski, Wojciech; Stayman, J. Webster; Xu, Jennifer; Taguchi, Katsuyuki; Siewerdsen, Jeffrey H.
Spectral CT of the extremities with a silicon strip photon counting detector Proceedings Article
In: Hoeschen, Christoph; Kontos, Despina; Flohr, Thomas G. (Ed.): SPIE Medical Imaging, pp. 94120Z, International Society for Optics and Photonics 2015.
Links | BibTeX | Tags: Extremities, MBIR, Photon Counting, Spectral X-ray/CT, System Design
@inproceedings{sisniega2015spectral,
title = {Spectral CT of the extremities with a silicon strip photon counting detector},
author = {Alejandro Sisniega and Wojciech Zbijewski and J. Webster Stayman and Jennifer Xu and Katsuyuki Taguchi and Jeffrey H. Siewerdsen },
editor = {Christoph Hoeschen and Despina Kontos and Thomas G. Flohr},
url = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?doi=10.1117/12.2082092},
doi = {10.1117/12.2082092},
year = {2015},
date = {2015-03-01},
booktitle = {SPIE Medical Imaging},
pages = {94120Z},
organization = {International Society for Optics and Photonics},
keywords = {Extremities, MBIR, Photon Counting, Spectral X-ray/CT, System Design},
pubstate = {published},
tppubtype = {inproceedings}
}
2014
Zbijewski, Wojciech; Gang, Grace; Xu, Jennifer; Wang, Adam S.; Stayman, J. Webster; Taguchi, Katsuyuki; Carrino, John A.; Siewerdsen, Jeffrey H.
Dual-energy cone-beam CT with a flat-panel detector: effect of reconstruction algorithm on material classification. Journal Article
In: Medical physics, vol. 41, no. 2, pp. 021908, 2014, ISSN: 0094-2405.
Abstract | Links | BibTeX | Tags: CBCT, MBIR, Spectral X-ray/CT
@article{zbijewski2014dual,
title = {Dual-energy cone-beam CT with a flat-panel detector: effect of reconstruction algorithm on material classification.},
author = {Wojciech Zbijewski and Grace Gang and Jennifer Xu and Adam S. Wang and J. Webster Stayman and Katsuyuki Taguchi and John A. Carrino and Jeffrey H. Siewerdsen },
url = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC3977791},
doi = {10.1118/1.4863598},
issn = {0094-2405},
year = {2014},
date = {2014-02-01},
journal = {Medical physics},
volume = {41},
number = {2},
pages = {021908},
publisher = {American Association of Physicists in Medicine},
abstract = {PURPOSE Cone-beam CT (CBCT) with a flat-panel detector (FPD) is finding application in areas such as breast and musculoskeletal imaging, where dual-energy (DE) capabilities offer potential benefit. The authors investigate the accuracy of material classification in DE CBCT using filtered backprojection (FBP) and penalized likelihood (PL) reconstruction and optimize contrast-enhanced DE CBCT of the joints as a function of dose, material concentration, and detail size. METHODS Phantoms consisting of a 15 cm diameter water cylinder with solid calcium inserts (50-200 mg/ml, 3-28.4 mm diameter) and solid iodine inserts (2-10 mg/ml, 3-28.4 mm diameter), as well as a cadaveric knee with intra-articular injection of iodine were imaged on a CBCT bench with a Varian 4343 FPD. The low energy (LE) beam was 70 kVp (+0.2 mm Cu), and the high energy (HE) beam was 120 kVp (+0.2 mm Cu, +0.5 mm Ag). Total dose (LE+HE) was varied from 3.1 to 15.6 mGy with equal dose allocation. Image-based DE classification involved a nearest distance classifier in the space of LE versus HE attenuation values. Recognizing the differences in noise between LE and HE beams, the LE and HE data were differentially filtered (in FBP) or regularized (in PL). Both a quadratic (PLQ) and a total-variation penalty (PLTV) were investigated for PL. The performance of DE CBCT material discrimination was quantified in terms of voxelwise specificity, sensitivity, and accuracy. RESULTS Noise in the HE image was primarily responsible for classification errors within the contrast inserts, whereas noise in the LE image mainly influenced classification in the surrounding water. For inserts of diameter 28.4 mm, DE CBCT reconstructions were optimized to maximize the total combined accuracy across the range of calcium and iodine concentrations, yielding values of ∼ 88% for FBP and PLQ, and ∼ 95% for PLTV at 3.1 mGy total dose, increasing to ∼ 95% for FBP and PLQ, and ∼ 98% for PLTV at 15.6 mGy total dose. For a fixed iodine concentration of 5 mg/ml and reconstructions maximizing overall accuracy across the range of insert diameters, the minimum diameter classified with accuracy textgreater80% was ∼ 15 mm for FBP and PLQ and ∼ 10 mm for PLTV, improving to ∼ 7 mm for FBP and PLQ and ∼ 3 mm for PLTV at 15.6 mGy. The results indicate similar performance for FBP and PLQ and showed improved classification accuracy with edge-preserving PLTV. A slight preference for increased smoothing of the HE data was found. DE CBCT discrimination of iodine and bone in the knee was demonstrated with FBP and PLTV at 6.2 mGy total dose. CONCLUSIONS For iodine concentrations textgreater5 mg/ml and detail size ∼ 20 mm, material classification accuracy of textgreater90% was achieved in DE CBCT with both FBP and PL at total doses textless10 mGy. Optimal performance was attained by selection of reconstruction parameters based on the differences in noise between HE and LE data, typically favoring stronger smoothing of the HE data, and by using penalties matched to the imaging task (e.g., edge-preserving PLTV in areas of uniform enhancement).},
keywords = {CBCT, MBIR, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {article}
}
2013
Zbijewski, Wojciech; Gang, Grace; Wang, Adam S.; Stayman, J. Webster; Taguchi, Katsuyuki; Carrino, John A.; Siewerdsen, Jeffrey H.
Noise reduction in material decomposition for low-dose dual-energy cone-beam CT Proceedings Article
In: Nishikawa, Robert M.; Whiting, Bruce R. (Ed.): SPIE Medical Imaging, pp. 866819, International Society for Optics and Photonics 2013.
Links | BibTeX | Tags: CBCT, MBIR, Spectral X-ray/CT
@inproceedings{zbijewski2013noise,
title = {Noise reduction in material decomposition for low-dose dual-energy cone-beam CT},
author = {Wojciech Zbijewski and Grace Gang and Adam S. Wang and J. Webster Stayman and Katsuyuki Taguchi and John A. Carrino and Jeffrey H. Siewerdsen },
editor = {Robert M. Nishikawa and Bruce R. Whiting},
url = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?doi=10.1117/12.2008431},
doi = {10.1117/12.2008431},
year = {2013},
date = {2013-03-01},
booktitle = {SPIE Medical Imaging},
pages = {866819},
organization = {International Society for Optics and Photonics},
keywords = {CBCT, MBIR, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {inproceedings}
}
2012
Gang, Grace; Zbijewski, Wojciech; Stayman, J. Webster; Siewerdsen, Jeffrey H.
Cascaded systems analysis of noise and detectability in dual-energy cone-beam CT. Journal Article
In: Medical physics, vol. 39, no. 8, pp. 5145–56, 2012, ISSN: 0094-2405.
Abstract | Links | BibTeX | Tags: Analysis, Spectral X-ray/CT, Task-Driven Imaging
@article{Gang2012,
title = {Cascaded systems analysis of noise and detectability in dual-energy cone-beam CT.},
author = {Grace Gang and Wojciech Zbijewski and J. Webster Stayman and Jeffrey H. Siewerdsen },
url = {http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC3422357},
doi = {10.1118/1.4736420},
issn = {0094-2405},
year = {2012},
date = {2012-08-01},
journal = {Medical physics},
volume = {39},
number = {8},
pages = {5145--56},
publisher = {American Association of Physicists in Medicine},
abstract = {PURPOSE Dual-energy computed tomography and dual-energy cone-beam computed tomography (DE-CBCT) are promising modalities for applications ranging from vascular to breast, renal, hepatic, and musculoskeletal imaging. Accordingly, the optimization of imaging techniques for such applications would benefit significantly from a general theoretical description of image quality that properly incorporates factors of acquisition, reconstruction, and tissue decomposition in DE tomography. This work reports a cascaded systems analysis model that includes the Poisson statistics of x rays (quantum noise), detector model (flat-panel detectors), anatomical background, image reconstruction (filtered backprojection), DE decomposition (weighted subtraction), and simple observer models to yield a task-based framework for DE technique optimization. METHODS The theoretical framework extends previous modeling of DE projection radiography and CBCT. Signal and noise transfer characteristics are propagated through physical and mathematical stages of image formation and reconstruction. Dual-energy decomposition was modeled according to weighted subtraction of low- and high-energy images to yield the 3D DE noise-power spectrum (NPS) and noise-equivalent quanta (NEQ), which, in combination with observer models and the imaging task, yields the dual-energy detectability index (d(')). Model calculations were validated with NPS and NEQ measurements from an experimental imaging bench simulating the geometry of a dedicated musculoskeletal extremities scanner. Imaging techniques, including kVp pair and dose allocation, were optimized using d(') as an objective function for three example imaging tasks: (1) kidney stone discrimination; (2) iodine vs bone in a uniform, soft-tissue background; and (3) soft tissue tumor detection on power-law anatomical background. RESULTS Theoretical calculations of DE NPS and NEQ demonstrated good agreement with experimental measurements over a broad range of imaging conditions. Optimization results suggest a lower fraction of total dose imparted by the low-energy acquisition, a finding consistent with previous literature. The selection of optimal kVp pair reveals the combined effect of both quantum noise and contrast in the kidney stone discrimination and soft-tissue tumor detection tasks, whereas the K-edge effect of iodine was the dominant factor in determining kVp pairs in the iodine vs bone task. The soft-tissue tumor task illustrated the benefit of dual-energy imaging in eliminating anatomical background noise and improving detectability beyond that achievable by single-energy scans. CONCLUSIONS This work established a task-based theoretical framework that is predictive of DE image quality. The model can be utilized in optimizing a broad range of parameters in image acquisition, reconstruction, and decomposition, providing a useful tool for maximizing DE-CBCT image quality and reducing dose.},
keywords = {Analysis, Spectral X-ray/CT, Task-Driven Imaging},
pubstate = {published},
tppubtype = {article}
}
Gang, Grace; Zbijewski, Wojciech; Stayman, J. Webster; Carrino, John A.; Siewerdsen, Jeffrey H.
Theoretical framework for the dual-energy cone-beam CT noise-power spectrum NEQ and tasked-based detectability index Proceedings Article
In: Pelc, Norbert J.; Nishikawa, Robert M.; Whiting, Bruce R. (Ed.): SPIE Medical Imaging, pp. 83131J, International Society for Optics and Photonics 2012.
Links | BibTeX | Tags: Analysis, CBCT, Spectral X-ray/CT, Task-Driven Imaging
@inproceedings{gang2012theoretical,
title = {Theoretical framework for the dual-energy cone-beam CT noise-power spectrum NEQ and tasked-based detectability index},
author = {Grace Gang and Wojciech Zbijewski and J. Webster Stayman and John A. Carrino and Jeffrey H. Siewerdsen },
editor = {Norbert J. Pelc and Robert M. Nishikawa and Bruce R. Whiting },
url = {http://proceedings.spiedigitallibrary.org/proceeding.aspx?doi=10.1117/12.911817},
doi = {10.1117/12.911817},
year = {2012},
date = {2012-02-01},
booktitle = {SPIE Medical Imaging},
pages = {83131J},
organization = {International Society for Optics and Photonics},
keywords = {Analysis, CBCT, Spectral X-ray/CT, Task-Driven Imaging},
pubstate = {published},
tppubtype = {inproceedings}
}
Zbijewski, Wojciech; Stayman, J. Webster; Muhit, Abdullah Al; Yorkston, John; Carrino, John A.; Siewerdsen, Jeffrey H.
CT Reconstruction Using Spectral and Morphological Prior Knowledge: Application to Imaging the Prosthetic Knee Proceedings Article
In: Second Int. Conf. Image Form. X-ray Computed Tomography, pp. 434–438, 2012.
Links | BibTeX | Tags: Artifact Correction, Beam Hardening, Extremities, Known Components, MBIR, Metal Artifacts, Spectral X-ray/CT
@inproceedings{Zbijewski2012,
title = {CT Reconstruction Using Spectral and Morphological Prior Knowledge: Application to Imaging the Prosthetic Knee},
author = {Wojciech Zbijewski and J. Webster Stayman and Abdullah Al Muhit and John Yorkston and John A. Carrino and Jeffrey H. Siewerdsen },
url = {http://istar.jhu.edu/pdf/Zbijewski_KCR_CTMeeting2012.pdf},
year = {2012},
date = {2012-01-01},
booktitle = {Second Int. Conf. Image Form. X-ray Computed Tomography},
pages = {434--438},
keywords = {Artifact Correction, Beam Hardening, Extremities, Known Components, MBIR, Metal Artifacts, Spectral X-ray/CT},
pubstate = {published},
tppubtype = {inproceedings}
}